IMPACT-AI LAB

The IMPACT-AI Lab at York University, led by Dr. Divya Sharma, is dedicated to building intelligent, ethically grounded, and clinically impactful AI systems for biomedical research and healthcare. Our work bridges advanced machine learning methods, biological data science, and real-world medical decision-making. We collaborate closely with clinicians and researchers at the University Health Network (UHN), including Toronto General Hospital, Princess Margaret Cancer Centre, and the Schroeder Arthritis Institute. Our research spans diverse domains such as liver transplantation, osteoarthritis, mental health, and precision oncology. From predicting graft injury in liver transplant recipients to identifying multi-omic signatures of osteoarthritis progression and designing generative AI companions for mental health support, we harness AI to enable personalized, explainable, and equitable care. Our interdisciplinary team develops and applies deep learning, reinforcement learning, and generative AI methods across structured, unstructured, and multi-modal biomedical data. We are committed to building AI systems that not only perform but also integrate into clinical workflows, ensuring relevance, transparency, and real-world utility.